Sections
                          Review Questions
                      Review Questions
1.
A diploid cell has how many times the number of chromosomes as a haploid cell?
            - four times
 - half
 - one-fourth
 - twice
 
2.
The first level of DNA organization in a eukaryotic cell is maintained by which molecule?
            - cohesion
 - condensin
 - chromatin
 - histone
 
3.
What inherited feature, in specific combinations, determines an organism’s traits?
            - cell membranes
 - genes
 - proteins
 - RNA
 
4.
What are identical copies of chromatin held together by cohesin at the centromere called?
            - histones
 - nucleosomes
 - chromatin
 - sister chromatids
 
5.
Chromosomes are duplicated during what stage of the cell cycle?
- G1 phase
 - prophase
 - prometaphase
 - S phase
 
6.
Which of the following events does not occur during some stages of interphase?
            - DNA duplication
 - increase in cell size
 - organelle duplication
 - separation of sister chromatids
 
7.
Attachment of the mitotic spindle fibers to the kinetochores is a characteristic of which stage of mitosis?
            - anaphase
 - prophase
 - prometaphase
 - metaphase
 
8.
The fusing of Golgi vesicles at the metaphase plate of dividing plant cells forms what structure?
            - actin ring
 - cell plate
 - cleavage furrow
 - mitotic spindle
 
9.
What would be the outcome of blocking S phase of interphase?
- The cell would enter karyokinesis.
 - DNA replication would not occur.
 - Centrosomes would be duplicated.
 - The cytoskeleton would be dismantled.
 
10.
At which of the cell cycle checkpoints do external forces have the greatest influence?
- G1 checkpoint
 - G2 checkpoint
 - M checkpoint
 - G0 checkpoint
 
11.
If the M checkpoint is not cleared, what stage of mitosis will be blocked?
            - prophase
 - prometaphase
 - metaphase
 - anaphase
 
12.
Which protein is a positive regulator that phosphorylates other proteins when activated?
- p53
 - retinoblastoma protein (Rb)
 - cyclin
 - cyclin-dependent kinase (Cdk)
 
13.
Which negative regulatory molecule can trigger apoptosis if vital cell cycle events do not occur?
- p53
 - p21
 - retinoblastoma protein (Rb)
 - cyclin-dependent kinase (Cdk)
 
14.
What is the main prerequisite for clearance at the  checkpoint?
            - The cell has a reached a sufficient size.
 - The cell has an adequate stockpile of nucleotides.
 - An accurate and complete DNA replication has occurred.
 - Proper attachment of mitotic spindle fibers to kinetochores has occurred.
 
15.
What do you call changes to the order of nucleotides in a segment of DNA that codes for a protein?
            - proto-oncogenes
 - tumor suppressor genes
 - gene mutations
 - negative regulators
 
16.
Human papillomavirus can cause cervical cancer. The virus encodes E6, a protein that binds p53. Based on this fact and what you know about p53, what effect do you think E6 binding has on p53 activity?
            - E6 activates p53.
 - E6 protects p53 from degradation.
 - E6 mutates p53.
 - E6 binding marks p53 for degradation.
 
17.
What is a gene that codes for a positive cell cycle regulator called?
            - kinase inhibitor
 - oncogenes
 - proto-oncogenes
 - tumor suppressor genes
 
18.
Which molecule is a Cdk inhibitor or is controlled by p53?
            - anti-kinase
 - cyclin
 - p21
 - Rb
 
19.
Which eukaryotic cell cycle events are missing in binary fission?
            - cell growth
 - DNA duplication
 - karyokinesis
 - cytokinesis
 
20.
Which of the following statements about binary fission is false?
            - In both prokaryotic and eukaryotic cells, the outcome of cell reproduction is a pair of daughter cells, which are genetically identical to the parent cell.
 - Karyokinesis is unnecessary in prokaryotes because there is no nucleus.
 - Replication of the prokaryotic chromosome begins at the origin of replication and continues in both directions at once.
 - The mitotic spindle draws the duplicated chromosomes to the opposite ends of the cell followed by formation of a septum and two daughter cells.
 
21.
The formation of what structure, that will eventually form the new cell walls of the daughter cells, is directed by FtsZ?
            - contractile ring
 - cell plate
 - cytoskeleton
 - septum